Mutations & structural modifications - Redux

Maybe we can expand the concept of structure a bit. One area of mutation that recieved quite a bit of attention a while back was structural aspects of protein domains. Tranquility Base and I had a running discussion concerning the evolution of protein families and protein domains. Would anyone object to adding protein structure and evolution/mutational changes to the general topic of structure?One of the problems with mutation and larger structural changes is that the area is a VERY young field due to the complexity of the phenotypic blending of the particulate genotypes (are you reading this Syamsu?). Maybe we would get a larger and more fruitfull discussion if we broadened the scope. It's your call, Wounded you started the thread.------------------
"Chance favors the prepared mind." L. Pasteur
Taz

How about this one for eye development then. I actually read about this a while ago where they were doing some of the intial work on PAX 6. The alterations may be due to differential downstream effects and binding vs. a defect in the gene itself. I am sure that there is more up to date material, I will see what I can dig up later.------------------
"Chance favors the prepared mind." L. Pasteur
Taz