Register | Sign In


Understanding through Discussion


EvC Forum active members: 65 (9164 total)
3 online now:
Newest Member: ChatGPT
Post Volume: Total: 916,914 Year: 4,171/9,624 Month: 1,042/974 Week: 1/368 Day: 1/11 Hour: 0/1


Thread  Details

Email This Thread
Newer Topic | Older Topic
  
Author Topic:   Telomere Shortening.....
Quetzal
Member (Idle past 5902 days)
Posts: 3228
Joined: 01-09-2002


Message 7 of 14 (34621)
03-18-2003 8:32 AM
Reply to: Message 6 by mark24
03-18-2003 8:14 AM


Re: Thanks for the replies.
Well, yeah basically. Telomerase is a reverse transcriptase that uses RNA as a template for coding DNA segments. The whole thing revolves around repairing chromosomes, or at least the ends. Every time a chromosome replicates, the telomeres on the ends get shorter (apparently, at a point the shortness tells the cell to stop dividing) - IOW, this controls the "aging" of most cells. After x number of replications, the cells die. Cells with telomerase are essentially immortal. Germline cells, some single-cell eukaryotes, and some cancer cells manufacture telomerase.
All you need to do is figure out some way to develop an injectable, temporary telomerase gene into your existing chromosomes, and voila! Immortality.

This message is a reply to:
 Message 6 by mark24, posted 03-18-2003 8:14 AM mark24 has not replied

Replies to this message:
 Message 8 by Randy, posted 03-18-2003 8:45 AM Quetzal has replied

  
Quetzal
Member (Idle past 5902 days)
Posts: 3228
Joined: 01-09-2002


Message 9 of 14 (34623)
03-18-2003 8:52 AM
Reply to: Message 8 by Randy
03-18-2003 8:45 AM


Cancer
That too. c-myc oncogene expression increases 70% in human cell cultures treated with a retroviral-carried telomerase gene. Hey, if it was easy, everybody be doing it...

This message is a reply to:
 Message 8 by Randy, posted 03-18-2003 8:45 AM Randy has not replied

  
Newer Topic | Older Topic
Jump to:


Copyright 2001-2023 by EvC Forum, All Rights Reserved

™ Version 4.2
Innovative software from Qwixotic © 2024