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Author Topic:   DNA RNA and PNA?
mogplayer101
Junior Member (Idle past 5447 days)
Posts: 4
From: Canada
Joined: 05-25-2009


Message 1 of 3 (510033)
05-26-2009 10:25 PM


I know basically that rna is the basis or the creation of dna, and now there is a process of grafting synthetic dna onto the double helix, this synthetic form of dna is referred to as PNA, does anyone know much (or anything) about pna? i was really wondering how they could graft it to the helix.

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 Message 3 by kuresu, posted 05-27-2009 1:53 PM mogplayer101 has not replied

  
AdminNosy
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From: Vancouver, BC, Canada
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Message 2 of 3 (510042)
05-27-2009 3:03 AM


Thread moved here from the Proposed New Topics forum.

  
kuresu
Member (Idle past 2541 days)
Posts: 2544
From: boulder, colorado
Joined: 03-24-2006


Message 3 of 3 (510100)
05-27-2009 1:53 PM
Reply to: Message 1 by mogplayer101
05-26-2009 10:25 PM


Do you mean replacing one strand in the DNA double helix with one strand of PNA?
First of all, the helix is not some superstructure to which the molecules making up DNA are attached. Rather, that structure is the result of the shape the molecules take as they bind to each other.
However, in terms of attaching a strand of PNA to DNA, I presume it would be similar to how two DNA strands combine to form the double helix--hydrogen bonding of the bases and generally complementary base pairs (although mismatches are possible).
If I recall correctly, it is the hydrogen bonding that is actually responsible for the double helix shape.
Here's the wiki article:
Peptide nucleic acid - Wikipedia

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