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Author Topic:   The End of Evolution By Means of Natural Selection
Faith 
Suspended Member (Idle past 1474 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


(1)
Message 541 of 851 (557088)
04-22-2010 3:46 PM
Reply to: Message 537 by Blue Jay
04-22-2010 1:56 PM


No, NOT playing Atari. And think about mutations again
--- then the mechanistic discussion is over, and all we are discussing now is the consequences of these processes, which the Asteroids analogy captures sufficiently well for our utility.
No it doesn't.
Speciation can be as messy, as dynamic and as devastating as you want it to be, but, the consequences are still the same: isolated populations and, if mutation is included, subsequent and/or prior addition of genetic diversity.
When you finally accept that this is the case ...
I've never denied that this is the case. What I have said is that when you get mutations you STOP GETTING THE PROCESSES OF VARIATION FROM ISOLATION, SELECTION, DRIFT with the concomitant REDUCTION OF ALLELES THAT MAKES NEW VARIETIES AND SPECIES.
ADDITION DOES NOT MAKE NEW SPECIES, THE SELECTION PROCESSES MAKE NEW SPECIES.
With addition, with mutations, assuming they do anything functional or useful at all, you would only get a bunch of new traits scattered throughout the population that blur the character of that population, which means destroying a species you already had if it occurs at that point, you do NOT get the making of a new variety, let alone a species. For that to happen you need the reduction processes. Put all the mutations into it you like, you are NOT getting speciation that way.
In fact, think through what mutations actually do. You get ONE per individual, right? As many have said, a single isolated allele doesn't stand much of a chance in a large population. It's not going to do anything for the species at all, just displace another allele that was probably functioning just fine with many others like itself in the overall population. So then what, you're waiting around for one of the new mutations to get selected? How often does that happen? You are talking as if the incidence of mutations is some great number that should offset the reduction processes but in actual fact you all don't even think they do much when you get down to it. And even you all have to admit most of them are either deleterious or simply unfunctional. Are you getting all ends of your story together here ever?
Furthermore, when you DO get a mutation, it changes only the function of the gene it sits on. If it's a gene for color you get a new color. If it's a gene for beak or nose size you get a bigger or smaller beak or nose. Where are you ever going to get the mutations you need for macroevolution? You need a new GENE, not just an allele, for the difference between a feather and a scale. You need a new GENE, in fact probably many new genes, not just an allele, for the difference between a finger and a claw. Do mutations do this? So far all you've said is that they are the source of alleles.
we can proceed to discuss whether or not mutation rates can outpace selection rates.
It is NOT a matter of outpacing. See above.
If you do not accept this, then you can go back through the circle again (with someone else this time), or you can try to defend your obstinance in not accepting it, rather than simply claim that the evidence that we have provided is not there.
I'll happily defend my obstinance forever, thank you very much.
Edited by Faith, : No reason given.
Edited by Faith, : No reason given.
Edited by Faith, : No reason given.
Edited by Faith, : No reason given.
Edited by Faith, : No reason given.
Edited by Faith, : No reason given.

This message is a reply to:
 Message 537 by Blue Jay, posted 04-22-2010 1:56 PM Blue Jay has replied

Replies to this message:
 Message 544 by Dr Adequate, posted 04-22-2010 4:16 PM Faith has replied
 Message 557 by Taq, posted 04-23-2010 9:41 AM Faith has not replied
 Message 559 by Blue Jay, posted 04-23-2010 10:28 AM Faith has replied

  
Faith 
Suspended Member (Idle past 1474 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 542 of 851 (557091)
04-22-2010 4:03 PM
Reply to: Message 538 by Dr Adequate
04-22-2010 2:17 PM


Re: Mutations Revisited 2 - super-pac magic animals
In your fantasy world there seems to be nothing preventing evolution from having happened in the past just as scientists assert that it has done.
I've never denied evolution on the level of microevolution. That is all that has gone on in the past and it's going on today as well.

This message is a reply to:
 Message 538 by Dr Adequate, posted 04-22-2010 2:17 PM Dr Adequate has replied

Replies to this message:
 Message 543 by Dr Adequate, posted 04-22-2010 4:11 PM Faith has replied

  
Dr Adequate
Member (Idle past 314 days)
Posts: 16113
Joined: 07-20-2006


Message 543 of 851 (557094)
04-22-2010 4:11 PM
Reply to: Message 542 by Faith
04-22-2010 4:03 PM


Re: Mutations Revisited 2 - super-pac magic animals
I've never denied evolution on the level of microevolution.
But the point that I was making is that your ridiculous fantasies about genetics do not rule out macroevolution either. The way that you are being wrong about genetics does not actually rule out the inescapable fact that you are so desperate to deny.

This message is a reply to:
 Message 542 by Faith, posted 04-22-2010 4:03 PM Faith has replied

Replies to this message:
 Message 546 by Faith, posted 04-22-2010 4:43 PM Dr Adequate has replied

  
Dr Adequate
Member (Idle past 314 days)
Posts: 16113
Joined: 07-20-2006


(1)
Message 544 of 851 (557096)
04-22-2010 4:16 PM
Reply to: Message 541 by Faith
04-22-2010 3:46 PM


Re: No, NOT playing Atari. And think about mutations again
In fact, think through what mutations actually do. You get ONE per individual, right?
"Right"? No. Pathetically, stupidly, laughably wrong.
Please, please, please just go and learn something about genetics.
Did this never occur to you? You wish to lecture us on a subject which you have never studied. And you must be aware of this. You must know that you have never studied genetics, you're not actually insane. You're not delusional. Therefore, you know that you have never studied genetics.

This message is a reply to:
 Message 541 by Faith, posted 04-22-2010 3:46 PM Faith has replied

Replies to this message:
 Message 545 by Faith, posted 04-22-2010 4:42 PM Dr Adequate has replied

  
Faith 
Suspended Member (Idle past 1474 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 545 of 851 (557097)
04-22-2010 4:42 PM
Reply to: Message 544 by Dr Adequate
04-22-2010 4:16 PM


Re: No, NOT playing Atari. And think about mutations again
Excuse me but I got that information in THIS discussion, either this thread or the other one. If it's wrong then you contribute your information to it.
I'm also aware of the study that found 70 from parents. So you could be a nice guy and help me resolve the disparate information.
Hm?
Edited by Faith, : No reason given.

This message is a reply to:
 Message 544 by Dr Adequate, posted 04-22-2010 4:16 PM Dr Adequate has replied

Replies to this message:
 Message 549 by Dr Adequate, posted 04-22-2010 4:55 PM Faith has replied

  
Faith 
Suspended Member (Idle past 1474 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 546 of 851 (557098)
04-22-2010 4:43 PM
Reply to: Message 543 by Dr Adequate
04-22-2010 4:11 PM


Re: Mutations Revisited 2 - super-pac magic animals
Both the Flood scenario and the argument about reduced genetic diversity rule out macroevolution.

This message is a reply to:
 Message 543 by Dr Adequate, posted 04-22-2010 4:11 PM Dr Adequate has replied

Replies to this message:
 Message 548 by Dr Adequate, posted 04-22-2010 4:53 PM Faith has not replied
 Message 550 by PaulK, posted 04-22-2010 4:57 PM Faith has not replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 4.9


(1)
Message 547 of 851 (557100)
04-22-2010 4:52 PM
Reply to: Message 530 by Faith
04-22-2010 12:36 PM


Re: Mutations Revisited 2 - super-pac magic animals
Faith writes:
He's right, that is indeed what I had in mind though I was hesitant to spell it out.
The reason you didn't spell it out is because that isn't what you had in mind. The phrase you used was "built-in alleles," and you used it because you had no idea where these alleles were. You never even used words like "duplicate genes" or "chromosomes," let alone "ploidy."
He's now confirmed that it could work.
The words WK actually used were "totally unsupported mechanisms." He characterized the likelihood of someone like yourself proposing a reasonable scenario as "wildly improbable."
Faith writes:
Percy writes:
Especially since it would take something like, oh, I don't know, MUTATIONS to eliminate all the duplicate chromosomes, either gene-by-gene or all at once?
Why not? Destroying genetic material appears to be what mutations do.
"Destroying genetic material" is only what you think mutations do, it's not what they actually do. The reality is that mutations modify DNA and selection then operates on the resulting phenotype. Deleterious changes are selected against, beneficial changes are selected for, and relatively neutral changes are governed only by random chance.
There have been at most around 2000 generations of cats since the flood (I'm referring to the entire cat family). If cats, like humans, experince around 100 mutations per generation, and if cats, like humans, have around 3 billion nucleotides pairs in their DNA, then that's a total of 200,000 mutation-caused differences between the original cats from the ark and today's cats. If we assume point muations, then 200,000 mutations could only affect about .006% (that's 6 out of every 100,000 nucleotides) of the cat genome. That is far too tiny a percentage to destroy any significant amounts of genetic material, or even any at all, and especially not entire genes. My numbers were approximations, but they can't be too far off, so correct values would not produce the orders of magnitude larger values that you need.
Are there any examples of a chromosome in the midst of the gene-by-gene loss possibility of chromosome loss?
That would be interesting to know and if anyone knows it I would assume it would be WK.
Well, why don't we ask him? Hey, WK, are there any examples of chromosomes in the midst of losing their genes one by one, genes that sequencing reveals have copies on other chromosomes?
The question is rhetorical because it's not a realistic possibility. We know that no animal we've sequenced so far has had any duplicate chromosomes within the last 10,000 years at the very least, because mutation rates are far, far too slow to have destroyed the evidence that they'd been duplicates.
Another problem is that mutations come in many forms, but the most common are point mutations where a nucleotide is added, deleted or changed to one of the other 3 nucleotides. Given that deletion is no more likely than addition, how would duplicate genes ever disappear in just 4000 years? If genes averaged 1000 nucleotides each and if every mutation was a deletion, and if these mutations conentrated themselves on just a few genes, then in 4000 years you could delete 4 genes (I'm way oversimplifying the math, but the number of genes would be small and you get the idea).
All scenarios to explain the necessary higher diversity on the ark are going to appear to be wildly improbable and trivially wrong by the uniformitarian assumption based on what happens today.
Except that there's no uniformitarian assumption. Everything we think we know about biology comes from scientific study, not assumptions, and all the evidence tells us that things worked in the past pretty much the same way they work today.
Apologies for the sarcasm, I've already been Faith'd twice in the past 24 hours, and I despair at the careful explanations I'm going to have to devise for her Message 509 that she'll then not understand, which will make three times.
Well, I get "Percy'd" regularly here so let's call it a draw.
Except that "getting Faith'd" means that careful explanations that were ignored or not understood were traded for copious amounts of nonsense, while "getting Percy'd" means accurate information about the current understanding of science was provided. Clearly those "getting Faith'd" are getting the short end of the stick.
--Percy

This message is a reply to:
 Message 530 by Faith, posted 04-22-2010 12:36 PM Faith has replied

Replies to this message:
 Message 551 by Faith, posted 04-22-2010 5:41 PM Percy has replied

  
Dr Adequate
Member (Idle past 314 days)
Posts: 16113
Joined: 07-20-2006


Message 548 of 851 (557101)
04-22-2010 4:53 PM
Reply to: Message 546 by Faith
04-22-2010 4:43 PM


Re: Mutations Revisited 2 - super-pac magic animals
Both the Flood scenario and the argument about reduced genetic diversity rule out macroevolution.
Whereas the facts about genetics make macroevolution inevitable.
What's your point?

This message is a reply to:
 Message 546 by Faith, posted 04-22-2010 4:43 PM Faith has not replied

  
Dr Adequate
Member (Idle past 314 days)
Posts: 16113
Joined: 07-20-2006


Message 549 of 851 (557103)
04-22-2010 4:55 PM
Reply to: Message 545 by Faith
04-22-2010 4:42 PM


Re: No, NOT playing Atari. And think about mutations again
Excuse me but I got that information in THIS discussion ...
No you didn't.
If you would like to pretend that some post on this thread gave you this crazy idea, then I should like to see you actually cite the post that inspired that delusion. I enjoy a good laugh.

This message is a reply to:
 Message 545 by Faith, posted 04-22-2010 4:42 PM Faith has replied

Replies to this message:
 Message 569 by Faith, posted 04-24-2010 4:47 AM Dr Adequate has replied

  
PaulK
Member
Posts: 17828
Joined: 01-10-2003
Member Rating: 2.4


Message 550 of 851 (557104)
04-22-2010 4:57 PM
Reply to: Message 546 by Faith
04-22-2010 4:43 PM


Re: Mutations Revisited 2 - super-pac magic animals
quote:
Both the Flood scenario and the argument about reduced genetic diversity rule out macroevolution.
Since your argument assumes that speciation happens - and I've no reason to believe that your Flood scenario doesn't assume it as well - that is pretty obviously untrue. Speciation IS macroevolution by the scientific definition which is the only viable definition we have.

This message is a reply to:
 Message 546 by Faith, posted 04-22-2010 4:43 PM Faith has not replied

  
Faith 
Suspended Member (Idle past 1474 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 551 of 851 (557108)
04-22-2010 5:41 PM
Reply to: Message 547 by Percy
04-22-2010 4:52 PM


Re: Mutations Revisited 2 - super-pac magic animals
Hi Percy, I just caught a bit of your post and want to give a bit of an answer before I have to leave again.
You are right that I hadn't brought up polyploidy until recently here but I really wasn't sure if it contributed alleles or enough alleles to make an argument out of it beyond just saying that I'd considered it before.
And if you want evidence that I'd considered it before, here's just one post -- Message 25 -- from four years ago that shows it was on my mind then too, and there are other posts where it came up back then too that I found through searching for "polyploidy" in all forums under the name Faith:
EvC Forum: Search

This message is a reply to:
 Message 547 by Percy, posted 04-22-2010 4:52 PM Percy has replied

Replies to this message:
 Message 552 by Dr Adequate, posted 04-22-2010 6:33 PM Faith has not replied
 Message 556 by Percy, posted 04-23-2010 7:24 AM Faith has not replied

  
Dr Adequate
Member (Idle past 314 days)
Posts: 16113
Joined: 07-20-2006


(1)
Message 552 of 851 (557119)
04-22-2010 6:33 PM
Reply to: Message 551 by Faith
04-22-2010 5:41 PM


Re: Mutations Revisited 2 - super-pac magic animals
You are right that I hadn't brought up polyploidy until recently here but I really wasn't sure if it contributed alleles or enough alleles to make an argument out of it beyond just saying that I'd considered it before.
You don't know enough about genetics to know whether you can twist and distort it in order to make a pathetic bogus argument. I'm sure that you would if you could, but in fact while the grown-ups are discussing polyploidy you don't even know what error you need to commit in order to be wrong. Because you have never studied genetics and you have no idea what we're talking about.

This message is a reply to:
 Message 551 by Faith, posted 04-22-2010 5:41 PM Faith has not replied

  
RAZD
Member (Idle past 1435 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


(1)
Message 553 of 851 (557125)
04-22-2010 7:22 PM
Reply to: Message 536 by Iblis
04-22-2010 1:40 PM


Re: mutations as disease, yet causing speciation?
Actually Iblis ...
The reason for this is that horses have 32 chromosome pairs (64 chromosomes) while donkeys have only 31 pairs (62.) As a result, the mule only has 63 chromosomes, which don't pair up properly for further reproduction.
Two of the chromosomes in horses are fused to make a single chromosome in donkeys. It is possible to match up the two parts to the one for reproduction - that is how you get mules.
Similar between Chimps and Humans - we have a fused pair that they (and other apes) have as individual chromosomes.
The genes on the chronomosomes are still comparable when you line them up.
Chimpanzee genome project - Wikipedia
Chromosome fusion
Enjoy.

we are limited in our ability to understand
by our ability to understand
Rebel American Zen Deist
... to learn ... to think ... to live ... to laugh ...
to share.


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This message is a reply to:
 Message 536 by Iblis, posted 04-22-2010 1:40 PM Iblis has not replied

  
RAZD
Member (Idle past 1435 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 554 of 851 (557126)
04-22-2010 7:25 PM
Reply to: Message 522 by Wounded King
04-22-2010 10:08 AM


of course ...
Hi Wounded Knee,
Bear in mind that she doesn't seem to have any objection to something like mutation facilitating her fanciful hypotheses, she only seems to object to the existence of beneficial mutations which increase genetic variation in a population.
Of course, for they can always claim that it was a deleterious or disease mutation that caused the breakup of the super-pac ark animals.
Enjoy.

we are limited in our ability to understand
by our ability to understand
Rebel American Zen Deist
... to learn ... to think ... to live ... to laugh ...
to share.


• • • Join the effort to solve medical problems, AIDS/HIV, Cancer and more with Team EvC! (click) • • •

This message is a reply to:
 Message 522 by Wounded King, posted 04-22-2010 10:08 AM Wounded King has not replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 4.9


Message 555 of 851 (557134)
04-22-2010 9:17 PM
Reply to: Message 509 by Faith
04-21-2010 10:49 PM


Re: juggling alleles
Hi Faith,
I'll attempt to explain once again, but it would be much easier to explain things to you if you could admit to yourself that you don't really understand these things very well yet. For example, in this message you say that genes are preserved:
Faith writes:
I'm aware that every gene matches in my scenarios, Percy. Genes aren't lost, only alleles.
Then a little later in Message 530 in answer to my question about where all the extra genes of polyploid chromosomes went since most life has no polyploid chromosomes, you say the opposite, that genes are lost:
Why not? Destroying genetic material appears to be what mutations do. The remnants are possibly to be found among the junk DNA. Or just gone I guess since our genome is very empty compared to that of bacteria. 95% of our genome junk DNA? Lot of dead genetic material there.
So genes aren't lost in your scenario, unless of course you need to get rid of the polyploid chromosomes that you made up, in which case then of course genes are lost in your scenario.
Your misinterpretation of that passage in Wikipedia as meaning that mutations weren't a factor in speciation is another example of your lack of understanding.
Your misinterpretation of people in this thread as saying that mutations do not change "the character of a species" is yet another example of your lack of understanding.
Now, before you get up on your high horse again just accept for now that maybe you don't know everything you need to know yet and listen this time for once, because that's the only way you'll ever learn anything.
So we have parent and daughter populations. The original parent population had 26 genes A through Z and four alleles per gene 1 through 4. The daughter population has over time lost some alleles and only has two alleles per gene 3 through 4. Here are the chromosomes for Organism P from the parent population and organism D from the daughter population (I'm refining the example slightly):
Organism P:
-------------------------------------------------
| A1 | B3 | C2 | ... | X4 | Y2 | Z4 |
-------------------------------------------------

Organism D:
-------------------------------------------------
| A3 | B4 | C4 | ... | X3 | Y4 | Z3 |
-------------------------------------------------
Organism D does not have a single allele that an organism from the parent population couldn't have. It doesn't have any allele combinations that an organism from the parent population couldn't have. That's what it means to be genetically the same species.
Now, if you don't believe me then go ahead and play with the alleles in the chromosome for organism D and try to come up with allele combinations that could not occur in the parent population. It's not possible, because the daughter only has alleles that the parent population already has. If a parent sperm or egg combined with a daughter sperm or egg then the combination would be viable. Parent and daughter populations are mutually interfertile and still the same species.
Now let's change the example a little. Let's say that time goes by and the parent population loses all alleles 3 through 4 and now only has alleles 1 through 2. Now the parent and daughter populations have not a single allele in common. The parent population only has alleles 1 through 2, and the daughter population only has alleles 3 through 4. There is not a single allele in the parent population that the daughter population has, and conversely there is not a single allele in the daughter population that the parent population has. What would happen if you brought together sperm and egg from the two populations, say just for example these two:
Organism P:
-------------------------------------------------
| A1 | B2 | C2 | ... | X1 | Y2 | Z1 |
-------------------------------------------------

Organism D:
-------------------------------------------------
| A3 | B4 | C4 | ... | X3 | Y4 | Z3 |
-------------------------------------------------
Would they be viable? Of course, because two organisms from the original parent population could easily have had these allele combinations and would have been able to mate. So two organisms from different populations but with only genes and alleles that the original parent population had will also be able to mate.
Now I claimed that you were looking at things at the phenotype level, while you maintain that you *are* looking at things genetically, but you really aren't. Here's the relevant portion of your reply:
If it’s really MY scenario you have in mind, the populations with the individuals with those alleles you have designated are now isolated from one another by distance or geographic barrier or whatnot, and each organism is now breeding exclusively with the others in its own population. Generations are passing as inbreeding is pretty thoroughly mixing up the alleles allotted to the population as a whole, time is passing, drift is occurring, selection may be occurring, and each population is developing a new look from the new phenotypes emerging as the fewer alleles are combining in new proportions, a new look that distinguishes them from one another. At this point they are a new variety and reproductive isolation may also be reinforced behaviorly as well as geographically.
We can clearly see that you are claiming that new phenotypes emerge through allele reduction that are sufficiently significant to cause speciation, and you're ignoring the plainly true fact that genetically both populations must still be genetically compatible because both parent and daughter populations have all the genes of the original parent population, and they only have alleles from the original parent population.
You're also forgetting about selection. The polyploid genes that you claim are there but not expressed and that emerge from their polyploid hiding place through some unknown process will only be selected for if they are beneficial. This is the same problem you claim mutations have, but there is an unending supply of mutations since reproduction is never perfect, and every copying error is another mutation. The supply of polyploid genes is necessarily limited.
But even worse for your scenario is that what you claim is the most common method of speciation, this polyploid storage of extra alleles, has no evidence in the genome of any species so far as the evidence we have in our possession at this time.
--Percy

This message is a reply to:
 Message 509 by Faith, posted 04-21-2010 10:49 PM Faith has replied

Replies to this message:
 Message 580 by Faith, posted 04-24-2010 2:34 PM Percy has replied

  
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