Hmm...I would think it would be helpful if we understood how and if any entanglement occurs in such a dense environment. I would think that would be a place to look for possible major effects, but then again, maybe not.
It is easy to find major entanglement effects.
A physicist discovers some small scale entanglement effects. He publishes a research paper. That publishing involves the cutting down of trees and this has effects on the local climate near the forest. Lots of people are also involved, from editors to peer reviewers to printers to research journal readers.
That sure seems like a major entanglement effect to me.
I suggest that these kinds of effects are the
only major effects you are likely to find.