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Author Topic:   How does Complexity demonstrate Design
pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 126 of 321 (117753)
06-23-2004 1:31 AM
Reply to: Message 116 by almeyda
06-22-2004 10:58 PM


001110010101111000011110101
Almeyda, DNA is simple - the information it stores is complex. Kind of like binary code (lots of 0s and 1s) holding all of the data on your harddrive.
Also, very little is required to replicate DNA - a single protein can do the job. The irreducible complexity just doesn't hold water in this case. My understanding is that RNA-based systems are even simpler.
You don't need "elaborate decoding machinery" for DNA maintanence and replication. You need it for complete functioning cells as they now exist, but not simply to maintain and replicate DNA.

This message is a reply to:
 Message 116 by almeyda, posted 06-22-2004 10:58 PM almeyda has not replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 127 of 321 (117757)
06-23-2004 1:45 AM
Reply to: Message 107 by DarkStar
06-22-2004 11:13 AM


Science vs. Weasel
DarkStar writes:
can we arbitrarily dismiss the contrary findings of scientists merely on the basis that their work does not support our own set of beliefs?
would we not be obligated to give as much credence to an opposing piece of research as we would expect to receive when our research is viewed as contrary to the findings of another scientist?
based upon the legitimacy of the methodical science which was conducted?
Hi DarkStar,
Just wanted to make sure you know what "scientific findings" and "pieces of research" are. I wanted to clarify, since you posted two examples of what you claim is "legitimate methodical science." Unfortunately you only posted two reviews of findings, and biased ones at that.
You see, citing scientific findings generally means that you are citing actual original data, not just someone else's questionable interpretation of another's data. One of the most frustrating things in science is that as soon as you publish your data and interpretations, someone else inevitably hijacks and twists it to their own conclusions.
So in the future, please reference actual original papers, otherwise at least make sure you call them review or opinion pieces, rather than the results of "methodical science".
Thanks.

This message is a reply to:
 Message 107 by DarkStar, posted 06-22-2004 11:13 AM DarkStar has replied

Replies to this message:
 Message 135 by DarkStar, posted 06-23-2004 8:18 PM pink sasquatch has not replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 145 of 321 (118312)
06-24-2004 2:12 PM
Reply to: Message 139 by almeyda
06-24-2004 12:43 AM


Re: Let's take these one at a time.
Almeyda - quoting someone else making unsupported assertions is not evidence.
The copying is far more precise than pure chemistry could manageonly about 1 mistake in 10 billion copyings, because there is editing (proof-reading and error-checking) machinery, again encoded in the DNA.
Firstly, it is completely incorrect to state a single copy error rate. Different organisms have different proofreading and editing machinery, and therefore different error rates - even individual humans can have vastly different replicative error rates.
Secondly, environment plays a huge part in error accumulation. This is why people who smoke get lung cancer - they are causing errors in their DNA sequence, leading to tumor formation. But the same is true of many other enviromental insults, not just chemical, but including things like heat and sunlight.
Lest it be argued that the accuracy could be achieved stepwise through selection, note that a high degree of accuracy is needed to prevent ‘error catastrophe’the accumulation of ‘noise’ in the form of junk proteins.
The truth is, there is no need for proofreading for replication of DNA, so there is no reason to believe that "the first cell" had proofreading mechanisms.
Additionally, that very lack of proofreading would have allowed evolution to take place much faster, because the error rate was higher, leading to more mutations...
Also, some proofreading capability comes in the form of an additional domain on an existing protein that replicates DNA, so there is no reason to belief that it wasn't a modification by selection.
The claim that potential 'error catastrophes' would prevent evolution is absurd - surely they occurred and killed off many individual life forms. But he's attacking mutation in general - as if he's arguing that no mutations occur at all...
Which even you know is not true...

This message is a reply to:
 Message 139 by almeyda, posted 06-24-2004 12:43 AM almeyda has not replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 155 of 321 (118476)
06-24-2004 11:40 PM
Reply to: Message 153 by DarkStar
06-24-2004 9:33 PM


absolute
Logic and reason dictate that no absolute position should taken until absolute proof has been acheived.
Just for reference, (and maybe you are already aware of this), you'll be hard pressed to find a true scientist claim to have absolute proof of anything. Generally a scientific "Law" is considered proven, but even then new info can add caveats.
And a note on some earlier posts you made regarding dismissing another scientist's conclusions without repeating their experiments: Scientific experiments are commonly carried out incorrectly - either in the technical details or in the entire plan of the experiment (like forgetting to do proper control studies). In those cases it is completely logical to dismiss the conclusions, since the experiments they rest on are necessarily inconclusive.
(I think that was the nature of the criticism MrHambre was laying on your references, but I don't want to speak for him.)
Thanks.

This message is a reply to:
 Message 153 by DarkStar, posted 06-24-2004 9:33 PM DarkStar has not replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 284 of 321 (134967)
08-18-2004 1:49 PM
Reply to: Message 276 by yxifix
08-18-2004 10:30 AM


Re: The universal genetic code
You see? RNA can't be created without already existing DNA and DNA can't be created without already existing RNA. That was simple. You must agree.
Yxifix - what you describe is true for a fully formed eukaryotic cell, but is not true in general.
RNA and DNA can be created by simple chemical reactions requiring essentially none of the details you describe.
I routinely create enormous amounts of DNA and RNA in the lab using such a chemical reaction, which includes NO cells, and only a single enzyme.
As has been explained already by Ooooook!, some RNAs (as you describe also) can act as enzymes, and self-replicating RNAs have been created that require no other interacting molecules.
Here's full text of a peer-reviewed journal article that provides some background on how RNA can form by chemical reactions, and how UV light can act as a selective force to drive RNA evolution. It may not be the best reference but the full text was available....
Computer can be created by a man but without program can do absolutely nothing.
But what if an electromagnetic disturbance scrambled the hard drive, accidentally creating binary code for a small computer virus, which subsequently replicates, filling the hard drive with copies of itself, and thus information?
Then the computer would be "doing something."
The same as a cell can do absolutely nothing without DNA code.
Incorrect. Red blood cells don't have DNA code, but they transport oxygen throughout your body.
edited to fix link...
This message has been edited by pink sasquatch, 08-18-2004 01:53 PM

This message is a reply to:
 Message 276 by yxifix, posted 08-18-2004 10:30 AM yxifix has not replied

Replies to this message:
 Message 285 by MisterOpus1, posted 08-18-2004 1:58 PM pink sasquatch has replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 286 of 321 (134973)
08-18-2004 2:09 PM
Reply to: Message 285 by MisterOpus1
08-18-2004 1:58 PM


Re: The universal genetic code
Nevertheless, just for argument sake I'm still willing to stick with yxifix's argument that it's just simply impossible for life to come from a few proteins and RNA strands to where we are today.
I think most supporters of RNA-to-life abiogenesis would agree that it is quite a leap, but would disagree with "impossible" in favor of "improbable". However, if we are able to deduce that it happened, the probability does not matter.
But what I need now from yxifix is positive, verifiable, observable, and falsifiable evidence of his alternative theory of an Intelligent Designer starting it all.
I'd like to see any 'real' evidence from yxifix also, since he takes such a firm stance. Unfortunately I've only seen argument by analogy, followed by the false logic of not-evolution-therefore-intelligent-design.

This message is a reply to:
 Message 285 by MisterOpus1, posted 08-18-2004 1:58 PM MisterOpus1 has not replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 289 of 321 (135071)
08-18-2004 7:19 PM
Reply to: Message 288 by Ooook!
08-18-2004 6:50 PM


C & G
...all have simple codons (consisting of only C's and G's)... more complex codons, and longer biosynthetic pathways could be integrated at a later time-frame.
Ooook! - the "only C's and G's" idea is potentially exciting in a biochemical sense. Since C-G bonds are inherently more stable than A-T bonds, they could have acted to "stabilize" the relatively labile RNA (vs. DNA). Perhaps the A's and T's were a post-DNA expansion of repertoire, within the allowance of DNA stability?
Is the reference available on-line?

This message is a reply to:
 Message 288 by Ooook!, posted 08-18-2004 6:50 PM Ooook! has replied

Replies to this message:
 Message 290 by Ooook!, posted 08-18-2004 7:53 PM pink sasquatch has replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 291 of 321 (135254)
08-19-2004 1:05 PM
Reply to: Message 290 by Ooook!
08-18-2004 7:53 PM


Re: C & G
Thanks... the hypothesis looks quite interesting, I'll have to see what I think of the details when I have some time.

This message is a reply to:
 Message 290 by Ooook!, posted 08-18-2004 7:53 PM Ooook! has not replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 298 of 321 (135412)
08-19-2004 7:41 PM
Reply to: Message 294 by yxifix
08-19-2004 6:58 PM


Re: The universal genetic code
Again, you are describing RNA/DNA/protein relationships at the cellular biology level, where they are, indeed complex. At the biochemical level they are quite simple...
You have to show what is used when this enzymatic RNA is replicating itself. Eg. where is a template needed. You must surely know how each genetic replication works.
Easy. (Also, the same RNA sequence is the template and enzyme.)
The first paper (I believe) on self-replicating RNA.
A recent paper describing an RNA capable of synthesizing nucleotides (the building blocks of the RNA strand).
Another paper describing an RNA that acts as a polymerase, efficiently and accurately copying another RNA strand.
No protein or DNA needed.
RNA -> You are saying a designer is not required... but I'm saying a designer is required. You must surely know the process of creation of RNA molecule. Could you describe it please? So in order to continue in discussion you have to accept that intelligence was needed to create such molekule. Then we can carry on:
This is what is really exciting! The experiments above created the enzymatic RNAs capable of replicating RNA without designing them.
Instead, they made enormous libraries of short RNAs of random sequence, and then simple selected (sound familiar?) those with enzymatic activity.
They did NOT design the sequence, they simply filtered out the ones without activity.
Also, please address my points in my message #284, which you have ignored twice now, presumably because you have no way to refute them (consider this a challenge).
However, since you continue to use your computer experiment as proof, after I've given you a scenario to falsify it twice, I'll repeat the scenario here (for the third time):
But what if an electromagnetic disturbance scrambled the hard drive, accidentally creating binary code for a small computer virus, which subsequently replicates, filling the hard drive with copies of itself, and thus information and activity?
Thanks in advance for your reply to these points.

This message is a reply to:
 Message 294 by yxifix, posted 08-19-2004 6:58 PM yxifix has replied

Replies to this message:
 Message 303 by yxifix, posted 08-23-2004 6:12 AM pink sasquatch has not replied

pink sasquatch
Member (Idle past 6053 days)
Posts: 1567
Joined: 06-10-2004


Message 311 of 321 (136345)
08-23-2004 3:39 PM
Reply to: Message 304 by yxifix
08-23-2004 6:14 AM


(ignoring) The universal genetic code
yxifix-
I do not appreciate your strategy of ignoring the bulk of my posts, especially when I have answered one of your points, only to see you bring it up again with someone else without any comment or refutation in to me.
From your post to Ooook!:
yxifix writes:
Well, I'm talking about ribozyme engineering. Can you describe how was RNA molecule you are talking about created in a lab?
From my last post (the first half contains the refs, the second half the non-design based method for finding ribozymatic sequences):
pink sasquatch writes:
Easy. (Also, the same RNA sequence is the template and enzyme.)
The first paper (I believe) on self-replicating RNA.
A recent paper describing an RNA capable of synthesizing nucleotides (the building blocks of the RNA strand).
Another paper describing an RNA that acts as a polymerase, efficiently and accurately copying another RNA strand. No protein or DNA needed....
This is what is really exciting! The experiments above created the enzymatic RNAs capable of replicating RNA without designing them.
Instead, they made enormous libraries of short RNAs of random sequence, and then simple selected (sound familiar?) those with enzymatic activity.
They did NOT design the sequence, they simply filtered out the ones without activity.
Was there something you didn't understand that I could explain better?

This message is a reply to:
 Message 304 by yxifix, posted 08-23-2004 6:14 AM yxifix has replied

Replies to this message:
 Message 312 by NosyNed, posted 08-23-2004 3:57 PM pink sasquatch has not replied
 Message 314 by yxifix, posted 08-26-2004 5:34 AM pink sasquatch has not replied

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