Register | Sign In


Understanding through Discussion


EvC Forum active members: 59 (9164 total)
3 online now:
Newest Member: ChatGPT
Post Volume: Total: 916,929 Year: 4,186/9,624 Month: 1,057/974 Week: 16/368 Day: 16/11 Hour: 0/0


Thread  Details

Email This Thread
Newer Topic | Older Topic
  
Author Topic:   Digital Life Design—What a concept!
Fosdick 
Suspended Member (Idle past 5531 days)
Posts: 1793
From: Upper Slobovia
Joined: 12-11-2006


Message 1 of 13 (450996)
01-25-2008 12:56 PM


Craig Venter's lab succeeds in Digital Life Design (DLD). It announces the first synthesis of a bacterial genome and the development of DLD synthetic life:
quote:
...In June 2007 another major advance was achieved when JCVI researchers led by Carole Lartigue, Ph.D., announced the results of work on genome transplantation methods allowing them to transform one type of bacteria into another type dictated by the transplanted chromosome. The work was published in the journal Science, and outlined the methods and techniques used to change one bacterial species, Mycoplasma capricolum, into another, Mycoplasma mycoides Large Colony (LC), by replacing one organism’s genome with the other one’s genome.
Genome transplantation was the first essential enabling step in the field of synthetic genomics as it is a key mechanism by which chemically synthesized chromosomes can be activated into viable living cells. Today’s announcement of the successful synthesis of the M. genitalium genome is the second step leading to the next experiments to transplant a fully synthetic bacterial chromosome into a living organism and “boot up” the cell.
This connects to the Life! What a concept! thread (where a discussion of the EDGE book is ongoing) because that book addresses claims that life is digital. As such, for all of the deniers of digital life, here is an interesting EDGE discussion between Richard Dawkins and Craig Venter, under the subtitle, LIFE: A GENE-CENTRIC VIEW:
quote:
DAWKINS: It’s more than just saying you can pick up a chromosome and put it in somewhere else. It is pure information. You could put it into a printed book. You could send it over the Internet. You could store it on a magnetic disk for a thousand years, and then in a thousand years’ time, with the technology that they’ll have then, it would be possible to reconstruct whatever living organism was here now. What has happened is that genetics has become a branch of information technology. It is pure information; it’s digital information; it’s precisely the kind of information that can be translated digit-for-digit, byte-for-byte into any other kind of information.
~
VENTER: Biology is the ultimate nanotechnology and it can now be digitally designed and reconstructed.
Seems to me that Venter has made good on his claims.
Questions: Will DLD end at bacteria? Will it be a new evolutionary forces to deal with?
”HM

Replies to this message:
 Message 3 by Wounded King, posted 01-26-2008 8:18 PM Fosdick has replied

  
Fosdick 
Suspended Member (Idle past 5531 days)
Posts: 1793
From: Upper Slobovia
Joined: 12-11-2006


Message 5 of 13 (451246)
01-26-2008 9:59 PM
Reply to: Message 4 by molbiogirl
01-26-2008 9:41 PM


Spiffy!
molbiogirl writes:
... = extra spiffy.
Yeah, it sure is, mbg. Makes me want to go places where Ringo would like to step in and kick my ass around. I'm probable off the map with my reasoning on this, but I can't apprehend what the digital part of life really means. Should I assume then that the functional core of biological life is digital, rather than analog?
Go ahead and beat me up over this. But I can't help thinking these stupid thoughts.
”HM

This message is a reply to:
 Message 4 by molbiogirl, posted 01-26-2008 9:41 PM molbiogirl has replied

Replies to this message:
 Message 7 by molbiogirl, posted 01-26-2008 11:27 PM Fosdick has replied

  
Fosdick 
Suspended Member (Idle past 5531 days)
Posts: 1793
From: Upper Slobovia
Joined: 12-11-2006


Message 6 of 13 (451247)
01-26-2008 10:08 PM
Reply to: Message 3 by Wounded King
01-26-2008 8:18 PM


Counter-chiral life
WK writes:
...non standard chiral biological molecules one could eventually make a mirror image system of life, but I'm not sure why you would want to or if we could even understand the sterochemistry sufficiently to make it work.
Careful, Wounded. You put a meme like that out there and the tabloids will run with it. Who's to say that counter-chiral life wouldn't take us back to the Garden of Eden? Cure all our problems!
”HM

This message is a reply to:
 Message 3 by Wounded King, posted 01-26-2008 8:18 PM Wounded King has not replied

  
Fosdick 
Suspended Member (Idle past 5531 days)
Posts: 1793
From: Upper Slobovia
Joined: 12-11-2006


Message 8 of 13 (451346)
01-27-2008 11:38 AM
Reply to: Message 7 by molbiogirl
01-26-2008 11:27 PM


Re: Spiffy!
mbg writes:
Do you honestly not understand the digital nature of DNA or are you trolling again?
Look who's trolling now.
Ever since the 2008 Admin Massacre I've been trying to mend my ways, using the example set by Nem Jug. But, oh no! I gotta put up with more of your petty plinking. The fact is, madame molecular biologist, I've been debating digital life for some time now. For example, please see Message 26 of the The "Digital Code" of DNA.
So why don't you just lighten up a little and take Nem Jug's advice, along with a handful of Midol.
”HM

This message is a reply to:
 Message 7 by molbiogirl, posted 01-26-2008 11:27 PM molbiogirl has not replied

  
Fosdick 
Suspended Member (Idle past 5531 days)
Posts: 1793
From: Upper Slobovia
Joined: 12-11-2006


Message 13 of 13 (471359)
06-16-2008 11:17 AM
Reply to: Message 12 by AshsZ
06-15-2008 3:45 PM


Digital tampering
AshsZ writes:
It is interesting that "Digital Life Design" is the wordage being used - this technology, in a refined version, would be analogous to writing a computer program. While that description fits really well to the technology, wouldn't that mean that these "programs" would need to be made in such a way so as to remain static in design to maintain control over said program? If genetic evolution is allowed to function, the programs are going to change over time and lead to results which may or may not be known. DNA has a knack at evolving into potently effective structures in ways we dont fully understand - not to mention, some of the mechanisms we do know of that create evolution already reveal how little control we have over it and how feeble any attempt to predict it would be. I wonder if it is possible to remove the "evolution" action from DNA. Are there any life forms which its DNA has always been the same?
All life has the same DNA. Chemically, it's the same molecule. The only difference that matters is the arrangement of its nucleotides. And therein lies the digital code. By discovering it, and by manipulating it, you know damn well that the future will be full of genetic tampering. I don't think our imaginations are broad enough to comprehend the consequences.
”HM

This message is a reply to:
 Message 12 by AshsZ, posted 06-15-2008 3:45 PM AshsZ has not replied

  
Newer Topic | Older Topic
Jump to:


Copyright 2001-2023 by EvC Forum, All Rights Reserved

™ Version 4.2
Innovative software from Qwixotic © 2024