Well, I think you are confusing two things.
First, there are models which allows us in a simple way to find patterns in what we observe of the universe, and find useful ways to predict those patterns elsewhere. For example, we have models of how electical and magnetical fields work, and from that we can build computers. Since computer demonstrably exist, it is not a matter of opinion wether the model describes reality or not.
Your may have opinions on what the model tells you, but unless you can show objectively that it's incorrect, your opinions will not budge it.
What IS an opinion is any truths regarding what the whole thing actually is all about when you aren't satisfied by mere models, and want the real deal. For example, what does a quark look like, where can you find god, do we have a real soul, why does music sound so heavenly. Essentially, you will need to form your own way to observe the 'real' world. This is where you should search your own mind.
But with science, it has been demonstrated time and time again that everyone, regardless of opinion, can make observations and actually agree to some things, which is to me a quite good argument that the whole of reality isn't just a personal preference.