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Author Topic:   Potential falsifications of the theory of evolution
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 558 of 968 (601534)
01-21-2011 7:02 AM
Reply to: Message 542 by molbiogirl
01-20-2011 5:33 PM


Re: Shapiro's use of the word "intelligent"
Asking if there's a "guiding intelligence," referring to cells as "sentient beings," calling them "intelligent," seems like an open invitation to being misunderstood.
--Percy

This message is a reply to:
 Message 542 by molbiogirl, posted 01-20-2011 5:33 PM molbiogirl has not replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 564 of 968 (601651)
01-22-2011 5:00 PM
Reply to: Message 560 by shadow71
01-22-2011 4:08 PM


Re: The past five decades of research in genetics and molecular biology have brouRe: yawn
shadow71 writes:
See above paper, and the impressive list of papers he has written in re "natural genetic engineering"
The approach you're taking seems to be:
  1. Find someone who you think has a falsification argument against evolution.
  2. Convince everyone he's so wonderful that he must be right.
An approach you might consider is:
  1. Reach agreement with other participants about what Shapiro is actually saying.
  2. Discuss Shapiro's actual views to determine whether he actually has a falsification argument against evolution.
--Percy

This message is a reply to:
 Message 560 by shadow71, posted 01-22-2011 4:08 PM shadow71 has replied

Replies to this message:
 Message 575 by shadow71, posted 01-23-2011 7:42 PM Percy has replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 586 of 968 (601781)
01-24-2011 7:13 AM
Reply to: Message 575 by shadow71
01-23-2011 7:42 PM


Re: The past five decades of research in genetics and molecular biology have brouRe: yawn
shadow71 writes:
I posted Shapiro's views...
Other people seem to think that what you actually posted was your misinterpretation of Shapiro's views. People are not going to discuss the details and implications of what they feel is a misinterpretation, they're just going to continue pointing out that you're misinterpreting Shapiro. If you want to actually discuss Shapiro's views then you're going to have to reach a consensus with the other people here about what those views really are.
Shapiro has been critical of the field of biology for inappropriately insisting on evolution as a scientific orthodoxy rather than just one of many dynamic and changing scientific theories. He seems to derive this belief from decidedly incomplete observations of the creation/evolution controversy, taking no notice of the fact that this is an arena where scientists are forced to make simple and unnuanced claims because of the general lack of knowledge and familiarity with evolution of laypeople in general and fundamentalist Christians in particular. Scientists take it as a given that all fields of science are dynamic and changing, but this quality of "dynamic and changing" which evolution shares with physics and chemistry and cosmology and geology and all the other fields of science does not mean that these theories are in danger of being overturned or even just radically changed.
Both Shapiro and Koonin have chosen extreme ways of expressing their views which garner them attention, which is I guess what they want. If you really believe Shapiro thinks that, for example, cells are intelligent in the same way that people are intelligent, then send him an email and ask him about it: jsha@midway.uchicago.edu
--Percy

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 Message 575 by shadow71, posted 01-23-2011 7:42 PM shadow71 has not replied

Replies to this message:
 Message 587 by molbiogirl, posted 01-24-2011 11:53 AM Percy has seen this message but not replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 605 of 968 (601997)
01-25-2011 1:44 PM
Reply to: Message 599 by shadow71
01-25-2011 11:43 AM


Re: what gets turned on? what's new?
shadow71 writes:
For example if "random mutation" is found to be unable to change information in the cell to to allow one species to evolve into another species, would your theory of evolution still be true?
After all this discussion I have to assume that you know that random mutation can change the information in a genome, and that you're really focused on the part about discovering that random mutations cannot accumulate to create new species. This would be like knowing you could walk across the street but discovering that for some reason you couldn't walk across the country. Or it would be like knowing that objects fall but that given a deep enough hole that objects couldn't fall all the way to the center of the Earth. These would be be stunning discoveries.
The answer to your question is, "Yes." If it were discovered that random mutations cannot accumulate to cause species change then the underlying mechanism behind the origin of species would be gone, and evolution as we know it would be falsified. Given what we already know through observation and experiments this is about as likely as discovering that the sun really does orbit the Earth.
I am not equivocating between neo-Darwinism and the modern interpretation of the theory of evolution. I am saying that James Shapiro based upon his research wrote:
"hereditary variation arises from the NON-RANDOM action of built-in biochemical systems that mobilize DNA and carry out natural genetic engineering." (My emphasis}
If that is accurate...
Your interpretation isn't accurate. You won't make any progress by continuing to trot out one misinterpretation after another. Molbiogirl's link works now, read the paper, look at the table on page 16. Shapiro does at times express himself in ways that must sound like music to creationist ears, but if he were really saying what you think he's saying then all his colleagues would be calling him on it. But they're not, because you're misinterpreting him as saying something that he's really not.
--Percy
Edited by Percy, : Grammar.

This message is a reply to:
 Message 599 by shadow71, posted 01-25-2011 11:43 AM shadow71 has replied

Replies to this message:
 Message 637 by shadow71, posted 01-27-2011 3:37 PM Percy has seen this message but not replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 613 of 968 (602173)
01-26-2011 4:21 PM
Reply to: Message 612 by shadow71
01-26-2011 3:43 PM


Re: Shapiro's definition of nonrandom
Just picking one wrong thing at random:
shadow71 writes:
So I am of the opinion that Shapiro is expressing the opinion that the information processing and regulatory actions taken by the cells are an expression that there is intelligence in the cells and this is the major factor in evolution.
Shapiro does not believe cells are intelligent in the same way that humans are intelligent. This has been explained to you over and over nine ways from Sunday.
We're all aware that Shapiro expresses himself in ways that actually encourage creationist misinterpretation, but we've explained how you're misinterpreting him. You have to respond to those explanations instead of just repeating your misinterpretations. There's really nothing new we can add.
--Percy

This message is a reply to:
 Message 612 by shadow71, posted 01-26-2011 3:43 PM shadow71 has replied

Replies to this message:
 Message 619 by shadow71, posted 01-26-2011 7:28 PM Percy has replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 620 of 968 (602227)
01-26-2011 8:38 PM
Reply to: Message 619 by shadow71
01-26-2011 7:28 PM


Re: Shapiro's definition of nonrandom
shadow71 writes:
Shapiro does not believe cells are intelligent in the same way that humans are intelligent. This has been explained to you over and over nine ways from Sunday.
Where did I say in my post "human intelligence"?
Where in my post did I say "human intelligence"? I said in the same way that humans are intelligent, which is the standard of intelligence that creationists use when talking about intelligent design. Don't you remember the intelligent design argument, that only intelligence has ever been observed creating a design? They're referring to designs created by people, and they're arguing that the designer is intelligent in the same way that humans are intelligent.
To put a finer point on it, Shapiro is not talking about the kind of intelligence as intended by the word "intelligent" in the term "intelligent design." He's using the term intelligence in a very uncommon way that leaves him open to misinterpretation by creationists like yourself. He's using the term intelligent (who knows why) to describe natural evolutionary processes. He's not endorsing intelligent design. If you think otherwise, send him an email. Invite him here to explain to everyone discussing with you how wrong we all are.
--Percy

This message is a reply to:
 Message 619 by shadow71, posted 01-26-2011 7:28 PM shadow71 has seen this message but not replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 623 of 968 (602268)
01-27-2011 6:38 AM
Reply to: Message 622 by Bolder-dash
01-27-2011 3:34 AM


Re: What a mess, shadow
Bolder-dash writes:
Shadow has as much right as you do to separate Shapiro's data from Shapiro's opinion.
I think everyone here would be delighted if Shadow would switch to discussing Shapiro's data instead of misinterpreting his writings.
Well, BS to that. Your theory said that it was random, unguided, extremely slow slight variations which have this phenomenal ability to accumulate over time. Now that it doesn't look at all like that...
Except that is does look exactly like that. For some reason Shapiro prefers to refer to some processes whose results cannot be predicted as non-random, and he likes to call cells intelligent because of some of the ways they can respond to environmental pressures, but neither his actual opinion nor his data support any aspect of intelligent design.
--Percy

This message is a reply to:
 Message 622 by Bolder-dash, posted 01-27-2011 3:34 AM Bolder-dash has replied

Replies to this message:
 Message 624 by Bolder-dash, posted 01-27-2011 7:30 AM Percy has replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 625 of 968 (602275)
01-27-2011 7:52 AM
Reply to: Message 624 by Bolder-dash
01-27-2011 7:30 AM


Re: What a mess, shadow
Bolder-dash writes:
but neither his actual opinion nor his data support any aspect of intelligent design.
Well, that's your opinion.
I suggest statements from him such as this say otherwise:
A major achievement of molecular biology has been the identification of molecules that cells use to acquire information about their chemical, physical, and biological environment and to keep track of internal processes. Many of the biological indicators include molecules produced by the cells themselves. Recognizing the chemical basis for sensing and communication constitutes a major advance in understanding how cells are able to carry out the appropriate actions needed for survival, reproduction, and multicellular development.
What aspect of intelligent design do you think this supports?
Furthermore Shapiro has a large list of what he calls "natural genetic engineering" but what someone else might just as easily label adaptive intelligent responses. (responses to qurom pheromones, dna damage, antibiotics, oxidative stress, opines, growth phases, heat shock, Extracyto-plasmic stress, genome reductions, sex phermones, aerobic starvation..etc..and these are just the ones we know of, imagine how many we don't).
Where Shapiro gets off claiming that this are all natural and completely unguided is anyones guess.
Given that these are all observed processes taking place naturally without any hint of guidance from anywhere, where is the evidence to claim otherwise?
And where does he feel these adaptive mechanisms originated? If evolution is controlled by these complex series of adaptive responses to environmental stimuli, then what brought about these adaptive responses---other adaptive responses?? Random mutations and natural selection? We give up?
The general answer is descent with modification and natural selection. The specific mechanisms that research has uncovered that carry out this process are complex.
Yours and or Shapiro's opinion that complex adaptive systems can somehow arise from complete random processes and then take over the evolutionary process and replace it with a new now non-random way...
I don't think anyone but you has described it in this way. What Shapiro calls non-random processes are not new. They might be more recently discovered than other mechanisms, but they aren't new. All the mechanisms of which we're now aware have been operating alongside one another for a long, long time. We will undoubtedly discover more (and more subtle) mechanisms that have been around for a long, long time.
Wow your religion really really requires an EXTRAORDINARY amount of faith.
My religion doesn't enter into it. If for you this is a religious discussion then you're in the wrong thread.
--Percy

This message is a reply to:
 Message 624 by Bolder-dash, posted 01-27-2011 7:30 AM Bolder-dash has not replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 635 of 968 (602332)
01-27-2011 3:13 PM
Reply to: Message 634 by Bolder-dash
01-27-2011 1:52 PM


Re: What a mess, shadow
Bolder-dash writes:
How can you demonstrate that Shapiro's findings don't suggest intelligent design.
What is it about Shapiro's findings that you think suggests intelligent design? Shapiro certainly doesn't think they do. Even minute examination of life's processes reveals nothing more than natural processes. Where in these processes do you see evidence for an intelligent designer? In their complexity? That's just the old tired claim of intelligent design, that life is too complex to have risen and evolved naturally. None of the evidence that would be apparent if an intelligent designer were at work, such as non-nested relationships between at least some species, or novelty arising in a single generation, has ever been observed. Shapiro certainly offers no help for intelligent design.
Creationists are latching onto Shapiro because he expresses himself in ways that they interpret as supportive of intelligent design. The reality is that Shapiro doesn't support intelligent design, and that's because his research doesn't support intelligent design. What his research does suggest to him is that the mechanisms of evolution are so far beyond what was originally conceived in the 1920's when the modern synthesis between Darwinian evolution and genetics arose that he has come to believe that it should be replaced with a more varied and nuanced framework. Most others disagree, pointing out that the 80 year old framework *has* changed a great deal and has already incorporated the ideas he enumerates.
With Darwinian concepts you could argue for completely unguided randomness...
Mutation is random, selection is not. Evolution includes both mutation and selection and cannot be described as "completely unguided randomness." In Message 624 you listed a bunch of processes that you labeled "adaptive intelligent responses" (I've edited this to make it more readable):
Bolderdash in Message 624 writes:
  • qurom pheromones
  • dna damage
  • antibiotics
  • oxidative stress
  • opines
  • growth phases
  • heat shock
  • Extracyto-plasmic stress
  • genome reductions
  • sex phermones
  • aerobic starvation
If the effect of any of these on the genome is non-random then you should be able to tell us what that effect will be. Pick one or two and tell us the specific changes they will cause to the genes of individuals. You won't be able to do this because when Shapiro says non-random he doesn't mean guided and certainly not deterministic.
On your final point about IDsts wanting to create a God where knowledge doesn't exist I just don't buy that argument. You have a choice of two: randomness or guidance (unless you can somehow come up with a third choice).
You've already made a few wrong choices. Your first wrong choice was in deciding to continually mischaracterize evolution as random. Mutations are random, selection is not.
Your second wrong choice is in thinking of the issue as either/or. It's not. The issue is following the evidence where it leads. When we examine life all we see is matter and energy following known laws of chemistry and physics.
Your third wrong choice is equating complexity with design. Cars and computers are examples of complexity designed by people. Kangaroos and kumquats are examples of complexity designed by nature.
--Percy

This message is a reply to:
 Message 634 by Bolder-dash, posted 01-27-2011 1:52 PM Bolder-dash has replied

Replies to this message:
 Message 655 by Bolder-dash, posted 01-28-2011 1:28 AM Percy has replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 656 of 968 (602402)
01-28-2011 2:58 AM
Reply to: Message 655 by Bolder-dash
01-28-2011 1:28 AM


Re: What a mess, shadow
Hi Bolder-dash,
You misunderstood or misread the question. The question asked about the specific genetic change. Your position is that the term "nonrandom" refers to guided or directed changes in the genome toward a specific goal resulting in improved competitive success in the current environment. But when asked for examples all you provided was:
Bolder-dash writes:
For Extracyto-plasmic stress the response will be an F plasmid Transfer
...
For Plant phenolics the response will be T-DNA transfer to plant cell in a A. tumefaciens bacteria
...
In E.Coli aerobic starvation will cause a Mu prophage activation.
None of these processes result in genomic changes directed toward any specific goal of improvement. The result is random with respect to reproductive success within the environment. Actual improvement to the genome will be through selection of these random changes across a population of organisms experiencing the same environmental stresses.
Care to try again? Or would you like to finally acknowledge that "nonrandom" in the way that Shapiro is using the term does not mean guided toward any specific goal?
What Shapiro actual means by nonrandom is that the when, where and type of mutations is to some degree under the control of molecular processes within the cell. What is not under cellular control is what the mutation will do and whether the mutation is beneficial or not.
--Percy

This message is a reply to:
 Message 655 by Bolder-dash, posted 01-28-2011 1:28 AM Bolder-dash has replied

Replies to this message:
 Message 659 by Bolder-dash, posted 01-28-2011 4:49 AM Percy has replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 658 of 968 (602405)
01-28-2011 3:33 AM
Reply to: Message 652 by shadow71
01-27-2011 7:23 PM


Re: RM & NS
shadow71 writes:
You won't listen to me and you won't listen to Taq.
So let's ask Shapiro.
Yes?
Thats fine with me. Let's ask him if he believes random mutation and natural selection are the major aspects of evolution ok?
Don't you want to ask Shapiro questions that would actually cast light on whether you're misunderstanding him or not? I think you need to ask him whether non-random means guided.
In answer to a question posed during a "chat" at William Dembski's ISCID (International Society for Complexity, Information and Design) Shapiro answered thusly (this is taken from James Shapiro Chat, and links like this are the kind of information Molbiogirl has requested that you supply when you're cut-n-pasting, and I think everyone else here feels the same way, in addition to making unambiguous which words are your own and which are not):
James Shapiro writes:
Non-random means that they operate under certain conditions (e.g. after genome damage or viral infection) and that these systems make characteristic kinds of changes. When a retrovirus-like element inserts in a new genomic location, it carries with it a defined set of regulatory signals that can affect the reading of nearby DNA sequences in very particular ways. This is an example of non-randomness. In addition, some changes (such as those in the immune system) can be targeted to specific locations by the presence of particular signals in the DNA or by activation of transcription. These phenomena show us that cells are capable of altering their genomes in non-random but not rigidly specified or pre-determined ways.
In other words, the mutations are random with respect to their effect or impact on fitness, but they are nonrandom with respect to the type of mutation and where in the genome they occur. Since they are random with respect to their effect they cannot be considered guided toward any particular goal. They are nonrandom in the sense that the types and locations of the mutations are more likely to have a relevant effect, but that effect would still be random with respect to fitness.
--Percy

This message is a reply to:
 Message 652 by shadow71, posted 01-27-2011 7:23 PM shadow71 has replied

Replies to this message:
 Message 666 by shadow71, posted 01-28-2011 11:38 AM Percy has seen this message but not replied
 Message 667 by molbiogirl, posted 01-28-2011 11:54 AM Percy has seen this message but not replied
 Message 672 by shadow71, posted 01-28-2011 12:15 PM Percy has replied
 Message 682 by Theodoric, posted 01-28-2011 1:24 PM Percy has seen this message but not replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


(1)
Message 660 of 968 (602410)
01-28-2011 6:57 AM
Reply to: Message 659 by Bolder-dash
01-28-2011 4:49 AM


Re: What a mess, shadow
Bolder-dash writes:
Percy, there is nothing random at all about the engineering that the cells are doing to counter specific environmental stresses.
You think the cells are doing engineering? What actual engineering do you see them doing? Engineering is just a colorful way of referring to the microbiological processes within the cell.
Regarding your claim that there is "nothing random" going on, the result of these processes is random with regard to fitness, so obviously there *is* something random going on. As has been explained to you, evolution is a combination of both random and nonrandom processes. Mutations are random with regard to fitness. Selection is nonrandom with regard to fitness. DNA replication during cell division is primarily nonrandom with regard to the sequences produced in the DNA copies. The mutational errors that occur during cell replication are random with regard to fitness, and they're also fairly random with regard to location and type.
This means that bold claims like this are wrong:
Now, the processes which control these genetic changes are NOT random!
Some processes, like selection and DNA replication, are not random. Some processes, like mutation type and their effect on fitness, *are* random. These random components are why you're unable to describe any specific genetic changes improving fitness that would be caused by your list of processes. They're why evolution isn't guided.
Question: Is it painful for you to watch the needle slowly drifting towards a guided world?
Clearly it is for Dr. A. He is clenching his butt cheeks so hard that he is seeing everyone as little men. You better watch out for him, I am afraid he will have an anal anyeurism soon.
It's stuff like this that causes moderators to ignore your complaints about ill treatment. You might try perusing rule 10 of the Forum Guidelines and leave the personal stuff out of your posts.
--Percy

This message is a reply to:
 Message 659 by Bolder-dash, posted 01-28-2011 4:49 AM Bolder-dash has replied

Replies to this message:
 Message 661 by Bolder-dash, posted 01-28-2011 11:00 AM Percy has replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 687 of 968 (602488)
01-28-2011 4:09 PM
Reply to: Message 661 by Bolder-dash
01-28-2011 11:00 AM


Re: What a mess, shadow
Bolder-dash writes:
Shapiro doesn't call these natural genetic engineering systems random (because they are not) I have explained to you exactly how a stress input is directly related to a specific adaptive response...
Explaining "how a stress input is directly related to a specific adaptive response" is precisely what you failed to do. What you said in Message 655 was:
Bolder-dash in Message 655 writes:
For Extracyto-plasmic stress the response will be an F plasmid Transfer
...
For Plant phenolics the response will be T-DNA transfer to plant cell in a A. tumefaciens bacteria
...
In E.Coli aerobic starvation will cause a Mu prophage activation.
There is no "specific adaptive response" anywhere in your answer. That's because none exists for you to explain. You can't explain something that has no reality. There is no avenue by which microbiological processes could know in advance what genomic changes would improve fitness. All they can do is randomly produce mutations from which natural selection can choose winners.
...and save your lectures about manners on this forum on this forum until you do something about the one who instigates the crap. You allow Dr A to say any meaningless, snarky crap he wants ad nauseum then you say I am not following the guidelines.
You are apparently blind to the high snark level in your own posts (your opening sentence, for example: "Until you understand what random means, you are going to continue to struggle with grasping the new evolutionary discoveries."). Dr Adequate is one of the most frequently suspended EvC members, and your continued participation in the same style will draw the same level of moderator attention.
The place to brings problems you're experiencing in discussion to the attention of moderators is Report Discussion Problems Here 3.0, something you've never done despite the many times I've pointed you to that thread.
--Percy

This message is a reply to:
 Message 661 by Bolder-dash, posted 01-28-2011 11:00 AM Bolder-dash has not replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 688 of 968 (602495)
01-28-2011 4:21 PM
Reply to: Message 686 by shadow71
01-28-2011 4:07 PM


Re: RM & NS
Hi Shadow,
I think you should ask questions that would more directly shed light on whether or not you're really misunderstanding what Shapiro is saying. We already know that Shapiro uses terms like intelligent and sentient and nonrandom in ways that are open to broad misinterpretation, and your questions will only draw answers that use those terms in the same easy-to-misinterpret way.
The question you want to ask Shapiro is whether his views about nonrandom change and intelligent sentient cells mean that evolution is guided.
--Percy

This message is a reply to:
 Message 686 by shadow71, posted 01-28-2011 4:07 PM shadow71 has replied

Replies to this message:
 Message 690 by shadow71, posted 01-28-2011 4:32 PM Percy has replied

Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 692 of 968 (602507)
01-28-2011 4:45 PM
Reply to: Message 672 by shadow71
01-28-2011 12:15 PM


Re: RM & NS
shadow71 writes:
Isn't Shapiro saying these non-random changes sometimes do have an effect on the organism that are beneficial?
Notice that you used the word "sometimes." You asked if the nonrandom changes could *sometimes* have a beneficial effect. It's the "sometimes" part that is the random component.
If a waiter sometimes brought you what you ordered and sometimes didn't and you never knew whether what the waiter brought next would be right or wrong, then you would say that he *sometimes* brought the right order. That means that whether or not be brings the right order is random. There is no way to predict in advance, except stochastically, which means you could only say something like, "There's a 34% probability that the waiter will bring the right dish."
Shapiro provides a specific example in that quote of what he means by non-random:
Shapiro writes:
he changes occur non-randomly in the sense that they follow certain predilections (e.g. some mobile elements insert near the start sites of transcription, others prefer to insert in protein coding sequences).
So lets consider a mobile element with a predilection for insertion near the start sites of transcription, and let's say that that's exactly what it does, it inserts near the start site of transcription of a specific gene. What will be the effect of that insertion?
The answer is that you can't know ahead of time. The effect of the insertion will be random. This random mutation was more likely to take place at the beginning of a transcription site because of the predilection of the mobile element responsible for it, but its effect upon the organism might be beneficial, it might be deleterious, it might be neutral, you don't know. And the organism's cells don't know either. Even if I agreed with Shapiro when he calls cells intelligent, that doesn't mean they're clairvoyant.
The only way to discover the effect of the insertion is to see if the resulting organism has improved, reduced or no change in fitness. And the only way to discover that is to let the organism and its descendants play out their lives and see what happens to that insertion mutation. If it propagates throughout the population then it must have been a pretty good mutation. If it disappears in a single generation (e.g., the organism dies without producing any offspring that inherit the mutation) then it probably wasn't so good. If the organism dies quickly after birth or is stillborn or spontaneously aborted then the mutation was probably pretty bad.
There's is no way to know in advance what the impact on fitness will be of the genomic change caused by Shapiro's so-called nonrandom mechanisms.
--Percy

This message is a reply to:
 Message 672 by shadow71, posted 01-28-2011 12:15 PM shadow71 has seen this message but not replied

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