But the "Mary's room" thought-experiment really doesn't address the point. The question it deals with is experience versus theoretical knowledge.
Now if you want something relevant I'd say that the results of the "split-brain" operation (severing the corpus callosum which is the main link between the two hemispheres of the brain) are relevant. In short the outcome is that the splitting the brain also splits consciousness (not entirely but close).
That's a major challenge to dualism.