Just asking the question, "Is evolution reversible?" reflects Doc's muddled understanding of evolution, but Dr Adequate probably captures the sense in which Doc intended the question. Probably Doc would consider the recently documented evolution of finches in the Galapagos as an affirmative, though completely unspectacular, answer to his question.
The question can also be addressed at the genetic level. The simplest mutation of a single nucleotide substitution can certainly be easily reversed in the next generation. Other types of mutations would have their own particular probability of reversal. A chromosome duplication could easily be reversed a generation later, but a chromosome loss would be almost impossible to reverse (except in cases where it was a duplicate of another chromosome).
--Percy