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Author Topic:   How do you define the word Evolution?
Taq
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Message 507 of 936 (806711)
04-27-2017 11:04 AM
Reply to: Message 496 by Dredge
04-27-2017 3:04 AM


Re: Dobzhansky
Dredge writes:
I know, but I like it ... and it's apt, considering the quasi-religious attachment atheists have to ToE.
What quasi-religious attachment?
That depends on your definition of evolution.
If we are using the scientific definition, then it is used in applied biology. In fact, I already gave you an example:
"We present a statistical graphical model to infer specific molecular function for unannotated protein sequences using homology. Based on phylogenomic principles, SIFTER (Statistical Inference of Function Through Evolutionary Relationships) accurately predicts molecular function for members of a protein family given a reconciled phylogeny and available function annotations, even when the data are sparse or noisy."
Protein molecular function prediction by Bayesian phylogenomics - PubMed
Evolution is used to predict protein function.
Evolution can also be used to predict which parts of genomes are functional.
Added by edit:
After writing the above, I suddenly thought of another good example of evolution being the foundation of applied medicine. That example is micro RNA's, or miRNA.
The process by which miRNA was discovered has everything to do with evolution. Scientists were puzzled by why they kept seeing these short ~20 base sequences that were very highly conserved between very different species. By applying evolution, it became apparent that these had to have a vital function that was very specific to their sequence which is why they were highly conserved.
As it turns out, miRNA is vital for cellular function, and its sequence is absolutely vital for that function. miRNA bind to the 3' end of messenger RNA through complementary bases (hence the vital role of the miRNA sequence) and downregulate the translation of that messenger RNA into protein. It is a form of post-transcriptional gene regulation. If you increase expression of an miRNA you will downregulate the production of proteins that correlate to that miRNA.
miRNA is now a focus of cancer and disease research. We can manufacture these short miRNA sequences, place them in little fat bubbles that bind to cells, and directly downregulate different genes, be they oncogenes or genes related to to the immune system. This research directly spawns from the discovery of miRNA by the application of evolution to genomic data.
Edited by Taq, : No reason given.
Edited by Taq, : No reason given.

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Taq
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Joined: 03-06-2009
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Message 508 of 936 (806716)
04-27-2017 11:08 AM
Reply to: Message 499 by Dredge
04-27-2017 3:29 AM


Re: If Not, What?
Dredge writes:
Ok, so the mutations appear to be independent of the antibiotic. In that case, all I see going on with antibiotic resistance is natural selection - bacteria mutate before and after the toxin, but it's still no more than natural selection. Natural selection alone can't account for how all life evolved from a common ancestor. so in this sense, antibiotic resistance is not an example of evolution.
In order for life to evolve from a common ancestor you have to get an accumulation of mutations over time that cause lineages to diverge from one another and from their ancestor. That is exactly what mutations and natural selection do. The bacterial population after mutation and selection in the presence of antibiotics has a different genome than the ancestral population. That population has at least 1 mutation that separates it from its ancestors, and probably more than 1. If you keep repeating the process over and over you get an accumulation of mutations over time.

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Taq
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Posts: 10085
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Member Rating: 5.1


(1)
Message 510 of 936 (806765)
04-27-2017 3:14 PM
Reply to: Message 501 by Dredge
04-27-2017 3:43 AM


Re: If Not, What?
Dredge writes:
Ok, there are aspects of evolutionary science that pertain to the real world, but their usefulness to the real world is the question.
You don't think understanding the history of biological species is useful in and of itself?
You seem to have a serious lack of curiosity. I would say that biologists are very curious as to how the world works, even if it doesn't have immediate application in the medical sciences. Fossils are VERY useful for figuring out why we see the species we do see, which is something that biologists are very curious about.
If you don't think that knowledge for the sake of knowledge is worth pursuing, then I pity you.

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


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Message 518 of 936 (806847)
04-28-2017 11:21 AM
Reply to: Message 517 by New Cat's Eye
04-28-2017 10:16 AM


Re: Dobzhansky
New Cat's Eye writes:
Not right now, no. I just don't think it is conclusive that ALL life has a common ancestor.
I would say that it is as conclusive as it gets. The cincher for me is transfer RNA (tRNA). These are short RNA molecules that have an anti-codon that binds to mRNA and an amino acid attached to them. These are the molecules responsible for turning an RNA 3 base codon into a protein.
There is simply no law requiring a strict correlation between an amino acid and the anti-codon of a tRNA. We see that the codon AUG results in a methionine in the protein, but there is no reason that an independent origin of life couldn't produce tRNA that uses AAG for methionine, or GGG.
The universal nature of codon usage just screams universal common ancestry, at least to me.
For example, they found some really weird microbes in a cave:
And I would bet all the money I have that they use the same sets of tRNAs that the rest of life uses.

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Taq
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Joined: 03-06-2009
Member Rating: 5.1


(1)
Message 520 of 936 (806856)
04-28-2017 12:23 PM
Reply to: Message 519 by NosyNed
04-28-2017 11:44 AM


Re: Multiple Origins
Nosyned writes:
Some years ago I read an article by a researcher pointing out that we may find that all life is clearly related because that is what we look for.
We may not notice something truly different. Another bush of life just might be so different we don't see it as alive or just haven't noticed. It may have been crowded out into strange unlikely (to us ) niches.
It doesn't seem all the likely to me either but it is an interesting thought.
A different set of tRNAs and codons would stick out like a sore thumb and couldn't be missed by biologists. Usage of different amino acids would also be an indication of a separate origin of life, and that would be obvious as well. A separate origin of life could also produce a very different genetic molecule that differs from DNA.
What we should see with different origins of life is fundamental differences in genetic systems, and it just isn't there.

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


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Message 552 of 936 (807221)
05-01-2017 12:30 PM
Reply to: Message 522 by Dredge
04-30-2017 12:35 AM


Re: If Not, What?
Dredge writes:
You can call antibiotic resistance and example of "evolution" if you like, but I fail to see how it can be used as evidence to support the theory that all life evolved from a common ancestor.
That screeching sound you hear is you dragging the goal posts.
The evolution of antibiotic resistance is an example of how the mechanisms of evolution work, namely the process of random mutation and natural selection.
Dredge writes:
In order for all life to have evolved from a common ancestor, mutations must produce limitless increases in the information stored in DNA.
That's completely false. Mutations only need to produce the limited information we see in living and fossil species.
The mutations seen in bacteria are like a merry-go-round ... they are constantly in motion but they don't actually go anywhere.
If I showed you the 40 million mutations that separate chimps and humans, could you determine which mutations were going somewhere? What criteria do you use to determine this?

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


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Message 553 of 936 (807222)
05-01-2017 12:32 PM
Reply to: Message 534 by Dredge
05-01-2017 12:34 AM


Re: If Not, What?
Dredge writes:
Please be advised that coming up with stories about how life was invented is nothing more than an historical curiosity.
Do you lack curiosity? It isn't worthwhile to sate our curiosity?
In other words, fossils are useful for embellishing a useless historical curiosity/theory that cannot be verified as fact. Big deal. Empty beer bottles are more useful than fossils.
Fossils are the facts that verify the theory of evolution.
Edited by Taq, : No reason given.

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


Message 554 of 936 (807223)
05-01-2017 12:34 PM
Reply to: Message 523 by Dredge
04-30-2017 12:38 AM


Re: If Not, What?
Dredge writes:
No.
Then you are using a double standard. Just because something is not directly applicable to medical science does not make it false.

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


Message 555 of 936 (807224)
05-01-2017 12:36 PM
Reply to: Message 530 by Dredge
05-01-2017 12:24 AM


Re: Dobzhansky
Dredge writes:
I am opposed to the theory that all life evolved from a commn ancestor because it 1) is a myth concocted from fake science, 2) it contradicts the Bible, 3) it has hijacked the science of biology and turned it into a propaganda vehicle for atheist theology.I am opposed to the theory that all life evolved from a commn ancestor because it 1) is a myth concocted from fake science, 2) it contradicts the Bible, 3) it has hijacked the science of biology and turned it into a propaganda vehicle for atheist theology.
First, you call evolution a myth because it contradicts your religious beliefs. You have demonstrated time and again that you don't even understand how science works.
Second, evolution has nothing to do with atheism. The majority of Christians wolrdwide accept evolution.

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(3)
Message 557 of 936 (807244)
05-01-2017 5:37 PM
Reply to: Message 543 by CRR
05-01-2017 6:18 AM


Re: Where are we now?
CRR writes:
You're not wrong about that, Dredge. The theory of evolution does include the Last Universal Common Ancestor (LUCA) unless the person you're talking to doesn't want that.
You don't seem to understand the relationship between historical contingencies and theory. Let's use gravity as an example. The theory of gravity explains the orbit of Mercury. However, the theory of gravity does not require the existence of Mercury in order to be correct. In the same way, the theory of evolution does not require a universal common ancestor. If there were multiple origins of life, and life evolved from those multiple ancestors, then that would be the theory. However, the theory does explain how the evidence points to a universal common ancestor with the evidence we do have.

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


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Message 579 of 936 (807330)
05-02-2017 10:49 AM
Reply to: Message 561 by Dredge
05-02-2017 2:17 AM


Re: Part of the problem?
Dredge writes:
According to Wiki, for example, ToE is "the process by which organisms change over time as a result of changes in heritable physical or behavioural traits". This sounds like microevolution to me.
All of the genetic differences between humans and chimps was produced by this process. Macroevolution is the accumulation of microevolutionary events. As an analogy, taking a single step is microevolution. Walking to the curb is macroevolution, and it works by repeating the process of taking a single step.
How can a sane discussion proceed about "evolution" or "the theory of evoltion" if you can't be sure what the hell the other person is referring to?
How can a sane discussion proceed when you refuse to listen to what other people are saying?

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


Message 580 of 936 (807331)
05-02-2017 10:50 AM
Reply to: Message 571 by Dredge
05-02-2017 6:20 AM


Re: If Not, What?
The DNA of an earthworm contains 10.465 infos; the DNA of a human being contains 3,356,298,112.2089 infos.
How did you arrive at those numbers?

This message is a reply to:
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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(3)
Message 581 of 936 (807334)
05-02-2017 10:59 AM
Reply to: Message 563 by CRR
05-02-2017 3:28 AM


Re: Part of the problem?
CRR writes:
Evolution is the theory that all the living forms in the world have arisen from a single source which itself arose naturally from an inorganic form.
As discussed before, the theory doesn't require an universal common ancestor.
"There is grandeur in this view of life, with its several powers, having been originally breathed into a few forms or into one; and that, whilst this planet has gone cycling on according to the fixed law of gravity, from so simple a beginning endless forms most beautiful and most wonderful have been, and are being, evolved."--Charles Darwin, "Origin of Species"
From the very start of the theory an universal common ancestor was not required. It just so happens that the evidence points to an universal common ancestor, so that is the conclusion that scientists have adopted.
and they are all correct in some sense and all wrong in some sense. Hence the confusion.
That is true of every single theory in science. As it turns out, human language can only approximate reality, so it will always fall short when describing reality. This is why the semantic arguments, which creationists are all too fond of, tend to fall flat. Instead of trying to understand what reality is like, ID/creationists want to obscure the subject by focusing on definitions for words.
I think it suits some people to leave it that way then they can say "Behold the Peppered Moth! That is an example of evolution. Hence we have proved that humans evolved from apes which evolved from LUCA."
I have yet to see anyone claim that the peppered moth proves that humans evolved from a common ancestor shared with other apes. Perhaps you could cite any of us saying that?
What the peppered moth does do is give a real world example of how the mechanisms of evolution work, namely the mechanism of random mutation and natural selection. The evidence for shared ancestry between humans and other species like chimps is found in things like endogenous retroviruses or transitional fossils.

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


Message 597 of 936 (807495)
05-03-2017 11:07 AM
Reply to: Message 582 by Dredge
05-03-2017 12:31 AM


Re: If Not, What?
Dredge writes:
What is the theory of evolution?
A large group of scientific explanations that attempt to model how populations of organisms change over time.

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Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


Message 598 of 936 (807496)
05-03-2017 11:09 AM
Reply to: Message 588 by Dredge
05-03-2017 1:58 AM


Re: Reality strikes again
Dredge writes:
The nested hierarchy of descent from common ancestors within the spacial-temporal matrix? Ah yes, I'd remember doing an assignment on this in Grade 5 in primary school. You seem to have overlooked that this is just a theory, so it's a bit much to expect special creation to explain some dubious evolutionary theory.
The nested hierarchy is an observed fact with reference to complex eukaryotes. The theory of evolution explains why we see this observed pattern of shared derived features.

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