Taq writes:
A pharmaceutical company has developed a compound that kills a broad spectrum of bacteria in standard cultures with a very low incidence of resistance. This same drug also kills bacteria that are resistant to other antibiotics. However, the scientists at the company have no idea if it is toxic in humans. What should they do first?
1. Expose plants to the drug.
2. Expose mice to the drug.
3. Expose chimps to the drug.
4. Expose humans to the drug.
5. Never test the drug and never release it while millions of people die from bacterial infections.
Start with mice, move on to more similar critters like pigs and chimps, use simulations to test as many possible human toxicity conditions as possible and if the results still look promising do a double blind test on human volunteers. Keep meticulous records.
Anyone so limited that they can only spell a word one way is severely handicapped!