The sexual selection barrier may apply when the living is easy, but when times get tough the selection of mates may be less picky when survival is at stake.
This was observed on the Galapagos Islands when two finch species interbred during a drought that did not interbreed before or after the drought.
So the blocking mechanism preventing mating between different species, barring environmental factors, is tied in with physical appearance or a surface level. As against a block on the cell level where different species may mate but produce no viable issue?
Wish I could explain that to my neighbour`s Dalmatian who repeatedly humps a concrete statue of Venus deMilo in his garden.