Natural slection acting on random mutation cannot account for the molecular underlying resistance to malaria by humans...
To join the dogpile: you are greatly mistaken, Shadow71. Google "hemoglobin C" and "malaria" until I get the time to open up my file cabinet and dig all my notes out. It's another single-base substitution in the sixth codon for the beta-chain of human hemoglobin. Demographics trace it to, most likely, a single mutation event about a millenium ago in what is now Burkina Faso. Not just the mutation, but much of the biochemistry behind why the mutation gives resistance to
Plasmodium is very well known.
"The wretched world lies now under the tyranny of foolishness; things are believed by Christians of such absurdity as no one ever could aforetime induce the heathen to believe." - Agobard of Lyons,
ca. 830 AD
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